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In this Buddhism religion history, I will cover its history in India.

In actual fact Buddhism covered almost the whole of Asia - excluding perhaps Russia. But I cannot cover all these details in a short article.

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

The Shakyamuni Buddha founded Buddhism through his enlightenment and teaching. He livd between 563 BC and 483 BC

Buddhism gained in popularity in India mainly during the reign of King Asoka (274-236BCE) because of

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

his patronage. Asoka is remembered in countries as far away as Japan because of his efforts to promote and spread Buddhism. Asoka played an important role in Buddhism religion history.

The doctrine which arose a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

a result of the original Buddha's teaching is Theravada Buddhism - or the Path of the Elders. It is also called Hinayana Buddhism.

Around and between the period 0-500 of the Christian era Mahayana Buddhism took s

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

hape in India. Mahayana is also called the Greater Vehicle as it contains many more skillful means to attain enlightenment as compared to the Theravada tradition.

So this is another important fact that must be me

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

tioned in a Buddhism religion history.

Alan Watts describes the evolution of Mahayana Buddhism as a response to the psychological needs caused by following the original Theravada doctrine.

There was also a need f

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

or transformation to meet the needs of new ages, new populations and different social circumstances. The old doctrine had become stale and was producing very few sages or Arahats.

Thus, a new literature came into

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

eing and this is one of the most magnificent outbursts of creative energy in human history. The realized master Nagarjuna lived in this period, which lasted for almost 500 years. During this period also Mahayana B

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

uddhism came in touch with non-Indian influence. In North-west India where it developed it came in touch with Greek culture as well as influences from the Mediterranean and the Iranian world. This is an important

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

tage in Buddhism religion history.

This incidentally rendered Buddhism fit for export outside India as for it to spread to other countries it first had to go through a preliminary phase of de-Indianization.

Anywa

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

y, Buddhism spread over the next 1500 years starting around the beginning of the Christian era. Mahayana has conquered the entire Northern half of the Buddhist world and the Buddhists of Nepal, Tibet, Mongolia, Ch

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ina, Korea and Japan are nearly all Mahayanists.

In India itself Buddhism came to an end about 1200 A.D. though is some States and districts such as Magadha, Bengal, Orissa and South India it lingered on for anoth

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

r 200 or 300 years.

The main reason for this decline and extinction was the Muslim invasions. These ruthless conquerors - with their zeal and hatred of idolatry - burned down flourishing monasteries and universiti

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

es in Sindh and Bengal and killed all the monks. This however was not the only reason as Hinduism and Jainism were subject to the same fury and stood their ground. The other reasons were:-

1) Hinduism had itself

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ssimilated much of Mahayana Buddhist thought the Buddhist were now not teaching anything different and new.

2) Buddhism failed to benefit the laity substantially and depended for its patronage mostly on kings. Whe

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

re such patronage was lacking, it declined. Jainism on the other hand had wealthy merchants patronizing them who considered it an honor to support ascetics. this is an important shortcoming of Buddhism in India an

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

must be mentioned in any Buddhism religion history.

3) Buddhism had lost its creative impulse and no new literature and doctrines were being developed at that time.

4) The other- world Buddhist monks did not con

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

sider the country of their residence very important. When they were unable to practice their monastic discipline they simply left for other countries such as Nepal, Tibet, China, etc. Thus the very reasons that le

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

to the spread of Buddhism to other countries in Asia caused its decline in India.

5) The Buddhist monks themselves regarded their own doctrine as having a limited shelf life. All is transient according to Buddhi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

sm and their own religion is not excluded. Thus when circumstances were such as existed at that time the only thing to do was to retire gracefully from the scene.

So this then is Buddhism religion history in India

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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